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дешевле","common.header:agitation-popup-content-go-2-app-title-alternative":"В приложении — выгоднее","common.header:agitation-thanks-page-go-2-app-description":"Следите за статусом в приложении","common.header:agitation-thanks-page-go-2-app-description-short":"Следите в приложении","common.header:agitation-thanks-page-go-2-app-title":"Не потеряйте заказ","common.header:agitation-tooltip-authorization-description":"Скидки на множество товаров\nстанут выше, а цены - ниже","common.header:agitation-tooltip-authorization-title":"Войдите в аккаунт","common.header:all-offers-title":"Все предложения","common.header:archive":"Архив","common.header:await-user-personal-data-card-btn":"Добавить данные","common.header:back-to-basket":"Вернуться в корзину","common.header:banner-aria-label":"Баннер","common.header:btn-text-go":"Перейти","common.header:carousel-pay-order-action-card-major-button":"К оплате","common.header:cart-entry-point-text-button":"Корзина","common.header:cart-treasure-title":"Давно в корзине","common.header:catalog-sins":"Каталог товаров","common.header:chat-with-support-profile-link":"Чат с поддержкой","common.header:chats":"Чаты","common.header:comparison-lists-profile-link":"Списки сравнения","common.header:documents-title":"Документы","common.header:empty-profile-touch-description":"Чтобы следить за статусом заказов, использовать бонусы и скидки","common.header:empty-profile-touch-title":"Войдите в аккаунт","common.header:exit-profile-link":"Выйти","common.header:express":"Express","common.header:favorite_category_descr":"Покупайте нужные товары со скидкой\n","common.header:favorite_category_title":"Любимая категория\n","common.header:favourites-profile-link":"Избранное","common.header:feedback_and_questions_profile_link":"Отзывы и вопросы","common.header:finances":"Финансы","common.header:fortune_wheel_descr":"Выигрывайте скидки и большие 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поиска","common.header:header-search-aria-label-search-btn":"Искать","common.header:header-search-aria-label-wipe-btn":"Стереть","common.header:header-search-lite-chip-text-promo":"Распродажа","common.header:header-search-lite-chip-text-univermag":"Универмаг","common.header:header-search-lite-placeholder-express":"Найти с быстрой доставкой","common.header:header-search-lite-placeholder-favorite":"Найти в избранном","common.header:header-search-lite-placeholder-promo":"Искать в акции","common.header:header-search-lite-placeholder-purches":"Найти в купленных товарах","common.header:header-search-lite-placeholder-search":"Искать товары","common.header:header-search-lite-placeholder-shop-in-shope":"Найти товары в магазине","common.header:header-search-placeholder-corner":"Искать в Универмаге","common.header:header-search-placeholder-default-desktop":"Найти товары","common.header:header-search-placeholder-default-redesigned":"'Я хочу 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Остеогенон таб. п/о
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Описание
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Остеогенон таб. п/о

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Рецептурный препарат
Тип препарата
Назначение
Форма выпуска
Страна-производитель
Франция
Инструкция
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Остеогенон таб. п/о
Остеогенон таб. п/о
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Инструкция
Бренд
Pierre Fabre Medicament Production
Тип препарата
лекарственный препарат
Рецептурный препарат
да
Органы и системы
опорно-двигательная система
Назначение
восстановление костей, нарушение кальциевого обмена, остеопороз
Показания к применению
Остеопороз различной этиологии (постменопаузальный, сенильный, обусловленный применением глюкокортикостероидов). Для регуляции кальциево-фосфорного баланса во время беременности и в период грудного вскармливания. В качестве дополнительной терапии при переломах костей.
Противопоказания
Повышенная чувствительность к компонентам препарата, тяжелая почечная недостаточность, гемодиализ, гиперкальциемия, гиперкальциурия, кальциевый нефролитиаз или кальцификация тканей, детский возраст.
Состав
Каждая таблетка, покрытая оболочкой, содержит:Ядро таблеткиАктивный компонент: соединение оссеин-гидроксиапатит (ОГС) - 830 мг (относится к сухой субстанции), соответствующее: оссеин - около 291 мг, состоящий из:неколлагеновых пептидов / протеинов - 75 мг, коллагенов - 216 мг;кальция гидроксифосфат (гидроксиапатит) - около 444 мг,включающий: кальций - 178 мг, фосфор - 82 мг;неактивная органическая фракция ОГС - около 95 мг,состоящая из липидов, кислоты лимонной, гликозоаминогликана, карбонатов в различных соотношениях в зависимости от конкретной партии животного сырья.Вспомогательные вещества: микрокристаллическая целлюлоза - 69 мг; кремния диоксид коллоидный - 10 мг; магния стеарат - 3 мг; крахмал картофельный - 15 мг (содержание воды в ОГС - около 58 мг).Оболочка:гипромеллоза - 9,0 мг; макрогол - 1,5 мг; железа оксид желтый - 0,5 мг; титана диоксид - 3,0 мг; тальк - 1,0 мг.
Способ применения и дозы
Препарат принимают внутрь, во время еды, запивая небольшим количеством воды. Таблетки не разжевывать.При остеопорозе: по 2-4 таблетки 2 раза в сутки.Для регуляции калъциево-фосфорного баланса во время беременности и в период грудного вскармливания: по 1-2 таблетки в сутки.В качестве дополнительной терапии при переломах костей у пациентов без патологии костной ткани: по 1-2 таблетки в сутки. У пациентов с патологией костной ткани дозу определяет врач, исходя из конкретной клинической ситуации.Продолжительность курса лечения определяется врачом.
Побочные действия
В очень редких случаях (<1/1 000 000) возможны: аллергические реакции; при длительном применении - гиперкальциемия, гиперкальциурия.
Фармакологическое действие
Препарат, влияющий на минерализацию костей (регулятор кальциево-фосфорного обмена).Остеогенон содержит необходимые для синтеза костной ткани компоненты и оказывает двоякое действие на метаболизм костной ткани: стимулирует остеобласты и ингибирует остеокласты.Кальций содержится в препарате в виде гидроксиапатита (в соотношении с фосфором 2:1), что способствует более полному его всасыванию из ЖКТ. Ингибирует выработку паратгормона и предотвращает гормонально обусловленную резорбцию костной ткани. Замедленное высвобождение кальция из гидроксиапатита обусловливает отсутствие пика гиперкальциемии.Фосфор, участвующий в кристаллизации гидроксиапатита, способствует фиксации кальция в кости и тормозит его выведение почками.Оссеин - органический компонент препарата, содержащий локальные регуляторы ремоделирования костной ткани (β-трансформирующий фактор роста, инсулиноподобные факторы роста I и II, остеокальцин, коллаген типа 1), которые активизируют процесс костеобразования и угнетают резорбцию костной ткани.β-трансформирующий фактор роста стимулирует активность остеобластов, повышает их количество, способствует выработке коллагена, а также ингибирует образование предшественников остеокластов.Инсулиноподобные факторы роста I и II стимулируют синтез коллагена и остеокальцина.Остеокальцин способствует кристаллизации костной ткани путем связывания кальция.Коллаген типа 1 обеспечивает формирование костной матрицы.
Фармакологическая группа
кальциево-фосфорного обмена регулятор
Форма выпуска
таблетки, покрытые оболочкой
Способ применения/введения
пероральный
Условия хранения
Препарат следует хранить в недоступном для детей месте при температуре не выше 30°С.
Передозировка
В настоящее время о случаях передозировки препарата Остеогенон не сообщалось.
Применение при беременности и кормлении грудью
БеременностьИмеющиеся данные о применении оссеин-гидроксиапатитного соединения во время беременности свидетельствуют об отсутствии мальформативной или фето/неонатальной токсичности. Проведенные доклинические исследования на животных не выявили репродуктивной токсичности. Препарат Остеогенон можно применять во время беременности при наличии клинических показаний.Грудное вскармливаниеОссеин-гидроксиапатитное соединение и, в частности, кальций потенциально могут проникать в грудное молоко. Согласно имеющимся данным, при применении препарата Остеогенон в рекомендованном диапазоне доз не ожидается какого-либо неблагоприятного влияния на ребенка, находящегося на грудном вскармливании. Препарат Остеогенон можно применять в период грудного вскармливания.
Влияние на способность управлять транспортом и механизмами
Специальные исследования не проводились. Случаев влияния препарата на способность к выполнению потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортными средствами, работа с движущимися механизмами) не выявлено.
Особые указания
У пациентов, предрасположенных к мочекаменной болезни, может потребоваться коррекция режима дозирования препарата в зависимости от лабораторных показателей. У пациентов с нарушениями функции почек следует избегать длительного применения высоких доз препарата. В состав препарата входят лишь следовые количества натрия хлорида, поэтому допустимо использование Остеогенона у пациентов с артериальной гипертензией.
Взаимодействие
Остеогенон замедляет всасывание препаратов железа, бисфосфонатов и антибиотиков группы тетрациклина, поэтому при одновременном применении с этими препаратами интервал времени между их приемом должен составлять не менее 4 ч.При одновременном применении Остеогенона с витамином D или тиазидными диуретиками врачу следует оценить степень риска развития гиперкальциемии вследствие усиления резорбции кальция.
Регистрационный номер
П N013182/01
Дата государственной регистрации
20.09.2019
Бренд
Pierre Fabre Medicament Production
Изготовитель
Pierre Fabre
Фасовщик
Pierre Fabre
Страна бренда
Франция
Страна-производитель
Франция
Название препарата
Остеогенон
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Остеопороз различной этиологии (постменопаузальный, сенильный, обусловленный применением глюкокортикостероидов). Для регуляции кальциево-фосфорного баланса во время беременности и в период грудного вскармливания. В качестве дополнительной терапии при переломах костей.
Повышенная чувствительность к компонентам препарата, тяжелая почечная недостаточность, гемодиализ, гиперкальциемия, гиперкальциурия, кальциевый нефролитиаз или кальцификация тканей, детский возраст.
Препарат принимают внутрь, во время еды, запивая небольшим количеством воды. Таблетки не разжевывать.
При остеопорозе: по 2-4 таблетки 2 раза в сутки.
Для регуляции калъциево-фосфорного баланса во время беременности и в период грудного вскармливания: по 1-2 таблетки в сутки.
В качестве дополнительной терапии при переломах костей у пациентов без патологии костной ткани: по 1-2 таблетки в сутки. У пациентов с патологией костной ткани дозу определяет врач, исходя из конкретной клинической ситуации.
Продолжительность курса лечения определяется врачом.
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Войдите в аккаунтИ тогда откроется избранное, а цены на Market могут стать ниже
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