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Market
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Клензит-С микросферы гель для наружного применения 30г
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Клензит-С микросферы гель для наружного применения 30г

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Рецептурный препарат
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Клензит-С микросферы гель д/нар. прим.
Клензит-С микросферы гель для наружного применения 30г
Задать вопрос
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ЗдравСити - сервис заказа и выдачи лекарств
Магазин•4.8 163.9K оценок
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Инструкция
Артикул Market
103543624610
Бренд
Glenmark
Тип препарата
лекарственный препарат
Рецептурный препарат
да
Органы и системы
кожа
Назначение
угревая болезнь
Показания к применению
Угревая сыпь.
Противопоказания
- Гиперчувствительность к компонентам препарата;- Одновременное применение с лекарственными препаратами, содержащими эритромицин;- Беременность;- Период грудного вскармливания;- "Клензит-С микросферы" не рекомендуется для применения у детей в возрасте до 18 лет (данные по эффективности и безопасности отсутствуют).С осторожностью:Дерматит, экзема, аллергические заболевания, одновременный прием миорелаксантов, одновременное применение препаратов, оказывающих раздражающее или подсушивающее действие на кожу. Если у Вас одно из перечисленных заболеваний, обязательно проконсультируйтесь с врачом.
Состав
1 г геля содержит:Действующие вещества:Адапален микросферический 10,0 мг, содержащий: адапален микронизированный 1,0 мг, метилметакрилата, изобутилметакрилата и этиленгликоля диметакрилата кроссполимер ("GANZPEARL GMP 0820") 9,0 мг.Клиндамицина фосфат 11.89 мг, эквивалент клиндамицину 10,0 мг.Вспомогательные вещества:Динатрия эдетат 0,5 мг, карбомер 940 (карбопол 940) 5,5 мг, пропиленгликоль 80,0 мг, метилпарагидроксибензоат 1,0 мг, феноксиэтанол 2,5 мг, полоксамер 407 1,0 мг, натрия гидроксид 1.0 мг, вода очищенная до 1 г.
Действующее вещество
Адапален+Клиндамицин
Способ применения и дозы
Наружно. Перед применением геля "Клензит-С микросферы" необходимо очистить и высушить кожу. Легким прикосновением равномерно наносить гель на пораженные участки кожи один раз в день перед сном, избегая попадания препарата в глаза, на губы и другие слизистые оболочки. Терапевтический эффект развивается через 1-4 недели, курс терапии 4-8 недель. Повторный курс лечения возможен после консультации с врачом. При появлении раздражения кожи лечение должно быть приостановлено до исчезновения признаков раздражения.
Побочные действия
Со стороны органов чувств: чувство жжения в глазах, раздражение век, зуд век, припухлость век, эритема в области век;со стороны пищеварительной системы: боль в животе, желудочно-кишечные расстройства (диарея, тошнота, рвота);со стороны кожных покровов: эритема, сухость и шелушение кожи, зуд, жжение, раздражение кожи, покалывание, усиление угревой сыпи, контактный дерматит, повышение продукции сальных желез, крапивница, аллергические реакции, солнечный ожог (фотосенсибилизация) в месте нанесения препарата, ощущение дискомфорта, болезненность кожи, припухлость кожи;прочие: фолликулит, вызванный грамотрицательной флорой;В редких случаях возможно развитие колита.
Фармакологическое действие
Комбинированный препарат для наружного применения. Действующими веществами препарата "Клензит-С микросферы" являются адапален и клиндамицин.Адапален - метаболит ретиноида, обладающий противовоспалительным действием и выраженной комедонолитической активностью (воздействует на открытые и закрытые комедоны), нормализует процессы кератинизации и эпидермальной дифференцировки.Механизм действия адапалена основан па взаимодействии со специфическими рецепторами эпидермальных клеток кожи. В результате действия адапалена происходит уменьшение связывания фолликулярных эпидермальных клеток в устье сально- волосяного фолликула и ускорение их отшелушивания, что уменьшает вероятность образования микрокомедонов. Адапален оказывает противовоспалительное действие in vivo и in vitro, воздействуя на факторы воспаления путем ингибирования миграции лейкоцитов в очаге воспаления и метаболизма арахидоновой кислоты. Подавляет хемотаксис и хемокинетические реакции полинуклеарных клеток у человека. Адапален в препарате Клензит-С микросферы заключен в микросферы. Микросферы представляют собой округлые микроскопические частицы, изготовленные из синтетических полимеров. Применение микросферной технологии снижает вероятность возникновения побочных эффектов и повышает стабильность, увеличивает биодоступность и эффективность лекарственного препарата. Микросферы обладают свойствами микрогубок, заключающих активное вещество и обеспечивающих его контролируемое во времени высвобождение после нанесения геля Клензит-С микросфсры на кожу в совокупности со снижением раздражения, улучшением фотостабильности и увеличением пенетрации препарата в кожу.Клиндамицина фосфат - бактериостатический антибиотик из группы линкозамидов, обладает широким спектром действия, связывается с 50S субъединицей рибосомальной мембраны и подавляет синтез белка в микробной клетке. Клиндамицин неактивен in vitro, но после нанесения на кожу быстро гидролизуется фосфатазами в протоках сальных желез с образованием клиндамицина, обладающего антибактериальной активностью. Показана чувствительность всех исследованных штаммов Propionibacterium acnes к клиндамицину in vitro (МПК 0,4 мкг/мл). После нанесения клиндамицина на кожу количество жирных кислот на поверхности кожи уменьшается с 14 % до 2 %.
Фармакологическая группа
средство лечения угревой сыпи
Форма выпуска
гель
Способ применения/введения
наружный
Условия хранения
В защищенном от света месте при температуре от 2 до 25°С. Хранить в недоступном для детей месте.
Передозировка
При наружном применении клиндамицин может всасываться в количествах, вызывающих системные эффекты. В случае передозировки показано проведение симптоматической и поддерживающей терапии. При случайном приеме препарата внутрь необходимо промыть желудок и немедленно обратиться к врачу.
Применение при беременности и кормлении грудью
В период беременности и при грудном вскармливании применение препарата противопоказано.
Влияние на способность управлять транспортом и механизмами
Не изучалось.
Особые указания
Чрезмерное нанесение геля не приводит к более быстрому или лучшему результату, в то же время могут отмечаться выраженные кожные реакции - покраснение, шелушение. Следует избегать попадания препарата на слизистую оболочку глаз и в полость рта. После применения препарата тщательно вымыть руки. При случайном контакте с чувствительными поверхностями (глаза, слизистые оболочки, повреждения на коже) следует обильно промыть данную область водой. В случае возникновения аллергических реакций или сильного раздражения применение препарата должно быть прекращено. Препарат не применяется при наличии повреждений кожи, экземы, а так же у пациентов с тяжелой угревой сыпью и при поражении больших площадей поверхности тела.Избегать прямых солнечных лучей, т.к. может появиться раздражение кожи. В случае длительного пребывания па солнце не наносить гель за день до этого, а также в день солнечной экспозиции и последующий день.При наружном применении клиндамицина случаи возникновения диареи и колита редки, тем не менее, следует проявлять осторожность, и при развитии выраженной или продолжительной диареи препарат следует отменить и при необходимости провести соответствующие диагностические и лечебные мероприятия.
Взаимодействие
Исследование взаимодействия с другими лекарственными препаратами не проводилось. Тем не менее, не следует одновременно применять другие ретиноиды или антибиотики для наружного применения, либо препараты с подобным механизмом действия.Поскольку адапален может вызывать местное раздражение кожи у некоторых пациентов, во избежание кумулятивного эффекта не рекомендуется одновременное применение с другими средствами, обладающими высушивающим или раздражающим эффектом (лечебные или абразивные мыла и моющие средства; мыла и косметические средства, обладающие подсушивающим эффектом; духи, этанолсодержащие средства и др.).Следует соблюдать осторожность при совместном применении с препаратами, оказывающими раздражающее или подсушивающее действие, в том числе содержащими серу, резорцинол или салициловую кислоту (возможно усиление побочного действия). Проявляет антагонизм с эритромицином. Так как системная абсорбция препарата при наружном применении незначительна, любые лекарственные взаимодействия с препаратами, применяемыми системно, маловероятны.Существует перекрестная устойчивость микроорганизмов к клиндамицину и линкомицину. Установлено, что клиндамицин нарушает нейромышечную передачу и, следовательно, может усиливать действие других миорелаксантов периферического действия, поэтому препарат следует применять с осторожностью у больных, получающих препараты данной группы.
Регистрационный номер
ЛП-003034
Дата государственной регистрации
16.06.2020
Бренд
Glenmark
Изготовитель
Glenmark
Фасовщик
Glenmark
Страна бренда
Индия
Страна-производитель
Индия
Название препарата
Клензит-С
Срок годности
23 мес.
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Угревая сыпь.
- Гиперчувствительность к компонентам препарата;
- Одновременное применение с лекарственными препаратами, содержащими эритромицин;
- Беременность;
- Период грудного вскармливания;
- "Клензит-С микросферы" не рекомендуется для применения у детей в возрасте до 18 лет (данные по эффективности и безопасности отсутствуют).
Наружно. Перед применением геля "Клензит-С микросферы" необходимо очистить и высушить кожу. Легким прикосновением равномерно наносить гель на пораженные участки кожи один раз в день перед сном, избегая попадания препарата в глаза, на губы и другие слизистые оболочки. Терапевтический эффект развивается через 1-4 недели, курс терапии 4-8 недель. Повторный курс лечения возможен после консультации с врачом. При появлении раздражения кожи лечение должно быть приостановлено до исчезновения признаков раздражения.

Отзывы

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30 оценок•6 отзывов
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Пока получается. Также витамины, бады, Омега 3 тоже снимает воспаления на 30%. Все вместе дало хороший результат уже через 2,5 месяца. ( на протяжении их были как улучшения так и рецидивы) \nМикросферы мало чем отличаются от С - поменьше побочки и более аккуратное корректное проникновение , больше для чувствительной кожи. Он более легкий. Хотя все они очень приятно разносятся, гель гладкой , не жирной структуры. Поскольку на сферы была хорошая скидка - попробовали. Все Ок!","rating":5,"advantages":"Клензит С рабочая мазь, в отличии от просто клензита или дифферина. В его составе кроме ретиноида адапалена еще и антибиотик клиндомицин. В сложных случаях нужен именно он, один ретиноид не работает. Хорошо показал себя , в итоге через 3 месяца ( 1 месяц из них был дифферин) лицо значительно очистилось. Утром азелоиновая не оч помогает , поменяли на Базирон АС, который подавляет выработку сала и сразу дело пошло на лад. 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Перед покупкой рекомендую обратиться к специалисту.\nВ качестве средства для лечения акне - рекомендую. Улучшения кожи есть.","date":"14 января 2023"},"ri_367558210":{"reviewId":"367558210","disadvantages":"Т.к у нас ребёнок аллергетик , мазь вызывает покраснение лица .\nПоэтому пьём препараты от аллергии.","reviewDate":"1736231068848","author":{"nickname":"Ателье ,,Olise\"","transition":{"params":{"publicId":"3jr1yjyq5gcaf276ekx6xj9kt4","title":"Ателье ,,Olise\"","isPreview":true},"type":"userPublicProfile"},"publicId":"3jr1yjyq5gcaf276ekx6xj9kt4","isPublicProfile":false,"analyticsData":{"uid":"462507177"},"isAnonymous":false,"isMyProfile":false,"avatarMediaItemId":"mi_3677218687962960007"},"authorItem":"au_8640678726950149010","fixId":367558210,"media":[],"rating":5,"advantages":"Крем реально работает. 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Достоинства:Клензит С рабочая мазь, в отличии от просто клензита или дифферина. В его составе кроме ретиноида адапалена еще и антибиотик клиндомицин. В сложных случаях нужен именно он, один ретиноид не работает. Хорошо показал себя , в итоге через 3 месяца ( 1 месяц из них был дифферин) лицо значительно очистилось. Утром азелоиновая не оч помогает , поменяли на Базирон АС, который подавляет выработку сала и сразу дело пошло на лад. ( азеиновая не подавляет - в этом ее минус)
Недостатки:не заметили , одежду действительно можно испортить , но только те ткани , что с плохо закрепленными красителями) попадали на дорогие бренды - им хоть бы что. Узбекская пижама из хлопка, майка - разъел.
Комментарий:На опыте своего сына ( тяжелая степень акне , уже есть шрамики небольшие и были бесконечные огромные пастулы ( множество подкожных белых комедонов воспаляясь сливались в один огромный - конглобатный) дерматолог дал одну схему, она оказалась не оч рабочая , плюс мы хотели избежать 8 месячного приема акнекутана - очень много злых побочек , особенно мышцы/ кости , а сын проф.спортсмен ), поэтому я сама перерыла кучу литературы ( у меня образование био-хим) и в итоге подобрала хорошо работающие именно в его случае крема . Пока получается. Также витамины, бады, Омега 3 тоже снимает воспаления на 30%. Все вместе дало хороший результат уже через 2,5 месяца. ( на протяжении их были как улучшения так и рецидивы) Микросферы мало чем отличаются от С - поменьше побочки и более аккуратное корректное проникновение , больше для чувствительной кожи. Он более легкий. Хотя все они очень приятно разносятся, гель гладкой , не жирной структуры. Поскольку на сферы была хорошая скидка - попробовали. Все Ок!
Достоинства:Крем реально работает. Посоветовала дерматолог. Но при ежедневном ,несколько месяцев , уходе .
Недостатки:Т.к у нас ребёнок аллергетик , мазь вызывает покраснение лица . Поэтому пьём препараты от аллергии.
Комментарий:Помогает подростку от прищей.
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Войдите в аккаунтИ тогда откроется корзина, а цены на Market могут стать ниже
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